{"id":502,"date":"2026-03-31T23:14:57","date_gmt":"2026-03-31T23:14:57","guid":{"rendered":"https:\/\/primalre.dalult4.hostarmada.net\/newwebsite\/?post_type=product&p=502"},"modified":"2026-09-02T20:22:41","modified_gmt":"2026-09-02T20:22:41","slug":"ipamorelin","status":"publish","type":"product","link":"https:\/\/primalre.dalult4.hostarmada.net\/newwebsite\/product\/ipamorelin\/","title":{"rendered":"Ipamorelin"},"content":{"rendered":"

Selective Ghrelin Receptor Agonist | Growth Hormone Secretagogue Research Compound<\/h2>\n

For Research Use Only. Not for human or veterinary use. Not a drug, supplement, or food additive.<\/strong><\/p>\n

Intended exclusively for in-vitro and laboratory research by qualified investigators.<\/p>\n

Ipamorelin \u2013 10mg<\/strong>
A Selective Ghrelin Receptor Agonist for Growth Hormone Axis Research<\/p>\n

Category:<\/strong> Peptide Research Compounds \/ Endocrinology Research \/ GH Axis Biology<\/p>\n

\n

Disclaimer<\/h3>\n

ATTENTION:<\/strong> PrimalResearchLabs.com products are intended for laboratory research and in-vitro studies only. All information presented is for educational and research purposes related to scientific investigation.<\/p>\n

These products are strictly not<\/strong> for human or veterinary use, consumption, or diagnostic applications. They are not<\/strong> pharmaceuticals, food additives, or dietary supplements.<\/p>\n

By purchasing from PrimalResearchLabs.com, you acknowledge that you are a qualified researcher operating in a controlled laboratory environment. Adhere to all applicable local, state, and federal laws and regulations regarding handling and use of research chemicals. Use appropriate personal protective equipment (PPE) and follow laboratory safety protocols.<\/p>\n

\n

Biology<\/h3>\n

Ipamorelin is a synthetic pentapeptide growth hormone secretagogue<\/strong> that selectively binds to the ghrelin receptor (GHS-R1a), stimulating pulsatile growth hormone (GH) release in preclinical and clinical research models.<\/p>\n

It has been extensively studied for its high receptor selectivity and its ability to promote GH secretion without significantly increasing ACTH, cortisol, or prolactin levels compared with earlier GHRP compounds.<\/p>\n

Ipamorelin is of particular interest in endocrine and metabolic research due to its ability to preserve physiological GH pulse patterns while supporting downstream insulin-like growth factor-1 (IGF-1) signaling<\/strong> pathways. Its selectivity and favorable pharmacodynamic profile make it a valuable tool for in-vitro and in-vivo experimental design across growth hormone biology, metabolic regulation, and recovery-related studies<\/strong>.<\/p>\n

This product is intended solely for in-vitro and preclinical research use and is not<\/strong> for human or veterinary consumption.<\/p>\n

\n

Key Research Applications of Ipamorelin<\/h3>\n

1. Growth Hormone Secretion & Ghrelin Receptor Signaling<\/h4>\n

Ipamorelin demonstrates significant activity in GH axis studies through:<\/p>\n

    \n
  • Selective GHS-R1a Activation:<\/strong> Stimulates GH release through ghrelin receptor binding with minimal activation of non-target endocrine pathways.<\/li>\n
  • Pulsatile GH Secretion:<\/strong> Preserves physiologic GH release patterns in contrast to continuous stimulation models.<\/li>\n
  • Reduced Off-Target Hormonal Effects:<\/strong> Exhibits minimal impact on ACTH, cortisol, and prolactin secretion.<\/li>\n<\/ul>\n

    Supporting Studies:<\/strong>
    Raun, K. et al. \u2014 European Journal of Endocrinology<\/em>
    “Ipamorelin is a highly selective growth hormone secretagogue that stimulates GH release without significant effects on ACTH or cortisol secretion.”<\/em> \u25a0 PubMed \u2013 PMID: 9849825<\/p>\n

    \n

    2. GH\/IGF-1 Axis & Anabolic Signaling<\/h4>\n

    Investigated in downstream endocrine pathways through:<\/p>\n

      \n
    • IGF-1 Modulation:<\/strong> Increases circulating IGF-1 levels secondary to GH stimulation in research models.<\/li>\n
    • Protein Synthesis Signaling:<\/strong> Enhances anabolic signaling pathways associated with tissue repair and regeneration.<\/li>\n
    • Skeletal Muscle Research:<\/strong> Applied in studies examining endocrine support for muscle growth and recovery.<\/li>\n<\/ul>\n

      Supporting Studies:<\/strong>
      J\u00f8rgensen, J.O.L. et al. \u2014 Growth Hormone & IGF Research<\/em>
      “Growth hormone secretagogues stimulate GH release and downstream IGF-1 production while preserving physiologic secretion patterns.”<\/em> \u25a0 PubMed \u2013 PMID: 11553901<\/p>\n

      \n

      3. Metabolic Regulation & Lipid Metabolism<\/h4>\n

      Explored in metabolic pathway studies through:<\/p>\n

        \n
      • Lipolysis Support:<\/strong> Promotes fat metabolism via GH-mediated signaling pathways.<\/li>\n
      • Energy Regulation:<\/strong> Influences metabolic efficiency and substrate utilization in experimental models.<\/li>\n
      • Endocrine Metabolic Research:<\/strong> Used in studies evaluating GH-related metabolic outcomes.<\/li>\n<\/ul>\n

        Supporting Studies:<\/strong>
        Smith, R.G. et al. \u2014 Endocrine Reviews<\/em>
        “Growth hormone secretagogues regulate metabolic processes including lipolysis and energy homeostasis through GH-dependent mechanisms.”<\/em> \u25a0 PubMed \u2013 PMID: 15769903<\/p>\n

        \n

        Recommended Research Concentrations<\/h3>\n

        For laboratory research reference only. Not for human or veterinary use.<\/em><\/p>\n

        \n
        \n\n\n\n\n\n\n\n
        Research Model<\/th>\nSuggested Concentration<\/th>\nAdministration<\/th>\n<\/tr>\n<\/thead>\n
        In-vitro receptor assays<\/td>\n1\u2013100 nM<\/td>\nAssay buffer<\/td>\n<\/tr>\n
        GH secretion studies<\/td>\n1\u2013100 nM<\/td>\nCell culture media<\/td>\n<\/tr>\n
        Animal models (rodents, SC)<\/td>\n0.1\u20131 mg\/kg<\/td>\nInjection<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<\/div>\n
        \n

        Why Choose Primal Research for Your Ipamorelin Studies?<\/h3>\n
          \n
        • \u226598% HPLC-verified purity \u2014 critical for ghrelin receptor binding and GH secretion accuracy<\/li>\n
        • Independent third-party batch testing with COA available on request<\/li>\n
        • Lyophilized powder for maximum stability and long-term storage<\/li>\n
        • Available in 10mg quantity \u2014 supports both focused and extended endocrine research protocols<\/li>\n<\/ul>\n
          \n

          Storage & Handling<\/h3>\n
            \n
          • Store at -20\u00b0C<\/strong>, desiccated and protected from light<\/li>\n
          • Soluble in sterile water or bacteriostatic water<\/li>\n
          • Prepare fresh solutions prior to each experiment<\/li>\n
          • Avoid repeated freeze-thaw cycles<\/li>\n<\/ul>\n
            \n

            Technical Specifications<\/h3>\n
              \n
            • Compound:<\/strong> Ipamorelin<\/li>\n
            • Molecular Weight:<\/strong> ~711.85 g\/mol<\/li>\n
            • Molecular Formula:<\/strong> C38H49N9O5<\/li>\n
            • Purity:<\/strong> \u226598% (HPLC Verified)<\/li>\n
            • Form:<\/strong> Lyophilized powder \u2014 10mg<\/li>\n
            • Storage:<\/strong> -20\u00b0C, desiccated, light-protected<\/li>\n
            • Solubility:<\/strong> Soluble in sterile water or bacteriostatic water<\/li>\n
            • COA:<\/strong> Available per batch on request<\/li>\n<\/ul>\n
              \n

              Advance Your Endocrine Research<\/h3>\n

              Order your Ipamorelin 10mg today to support advanced research in growth hormone signaling, ghrelin receptor biology, and metabolic science<\/strong>.<\/p>\n

              Primal Research products are sold strictly for in-vitro and laboratory research use only. Not for human or veterinary consumption. Not intended to diagnose, treat, cure, or prevent any disease or condition. Purchasers are responsible for compliance with all applicable local, state, and federal regulations.<\/p>\n","protected":false},"excerpt":{"rendered":"

              Primal Research products are sold strictly for in-vitro and laboratory research use only. Not for human or veterinary consumption. Not intended to diagnose, treat, cure, or prevent any disease or condition. Purchasers are responsible for compliance with all applicable local, state, and federal regulations.<\/p>\n","protected":false},"featured_media":1001,"template":"","meta":{"_acf_changed":false},"product_brand":[],"product_cat":[79],"product_tag":[],"class_list":["post-502","product","type-product","status-publish","has-post-thumbnail","product_cat-research-blends","pa_packaging-5mg","first","instock","shipping-taxable","purchasable","product-type-variable"],"acf":[],"_links":{"self":[{"href":"https:\/\/primalre.dalult4.hostarmada.net\/newwebsite\/wp-json\/wp\/v2\/product\/502","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/primalre.dalult4.hostarmada.net\/newwebsite\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/primalre.dalult4.hostarmada.net\/newwebsite\/wp-json\/wp\/v2\/types\/product"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/primalre.dalult4.hostarmada.net\/newwebsite\/wp-json\/wp\/v2\/media\/1001"}],"wp:attachment":[{"href":"https:\/\/primalre.dalult4.hostarmada.net\/newwebsite\/wp-json\/wp\/v2\/media?parent=502"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/primalre.dalult4.hostarmada.net\/newwebsite\/wp-json\/wp\/v2\/product_brand?post=502"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/primalre.dalult4.hostarmada.net\/newwebsite\/wp-json\/wp\/v2\/product_cat?post=502"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/primalre.dalult4.hostarmada.net\/newwebsite\/wp-json\/wp\/v2\/product_tag?post=502"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}