{"id":523,"date":"2026-03-31T23:39:40","date_gmt":"2026-03-31T23:39:40","guid":{"rendered":"https:\/\/primalre.dalult4.hostarmada.net\/newwebsite\/?post_type=product&p=523"},"modified":"2026-09-02T20:31:26","modified_gmt":"2026-09-02T20:31:26","slug":"pt-141","status":"publish","type":"product","link":"https:\/\/primalre.dalult4.hostarmada.net\/newwebsite\/product\/pt-141\/","title":{"rendered":"PT-141"},"content":{"rendered":"

PT-141 | Melanocortin Receptor Agonist for Neuroendocrine & CNS Research<\/strong><\/span><\/h2>\n

\u25a0 For Research Use Only. Not for human or veterinary use. Not a drug, supplement, or food additive.
Intended exclusively for in-vitro and laboratory research by qualified investigators.<\/p>\n

PT-141 \u2013 10mg<\/strong>
Category:<\/strong> Peptide Research Compounds \/ Neuroscience Research \/ Melanocortin System Biology<\/p>\n

\n

Disclaimer<\/strong><\/span><\/h3>\n

ATTENTION: PRIMALRESEARCHLABS.COM PRODUCTS ARE INTENDED FOR LABORATORY RESEARCH AND IN-VITRO STUDIES ONLY.<\/p>\n

All information presented on this site is for educational and research purposes related to scientific investigation.<\/p>\n

These products are strictly not for human or veterinary use, consumption, or diagnostic applications.<\/p>\n

They are not pharmaceuticals, food additives, or dietary supplements.<\/p>\n

By purchasing from PrimalResearchLabs.com, you acknowledge that you are a qualified researcher operating in a controlled laboratory environment and agree to follow all applicable local, state, and federal laws regarding the handling and use of research chemicals.<\/p>\n

Handle all materials with appropriate personal protective equipment (PPE) and laboratory safety protocols.<\/p>\n

\n

Biology<\/strong><\/span><\/h3>\n

PT-141 (Bremelanotide) is a synthetic peptide derived from melanocortin analogs, designed to selectively activate melanocortin receptors, particularly MC4R, in the central nervous system.<\/p>\n

Unlike peripheral-acting compounds, PT-141 primarily exerts its effects through central neuroendocrine pathways.<\/p>\n

It has been extensively studied in preclinical research for its ability to modulate hypothalamic signaling, influence behavioral responses, and interact with dopaminergic pathways.<\/p>\n

Its receptor specificity and central mechanism of action make PT-141 a valuable tool for in-vitro and in-vivo experimental design across neuroendocrine signaling, behavioral research, and melanocortin system studies.<\/p>\n

This product is intended solely for in-vitro and preclinical research use and is not for human or veterinary consumption.<\/p>\n

\n

Key Research Applications<\/strong><\/span><\/h3>\n

1. Melanocortin Receptor Signaling & Neuroendocrine Research<\/strong><\/span><\/h4>\n
    \n
  • MC4R Activation:<\/strong> Selectively stimulates melanocortin-4 receptors involved in central signaling pathways.<\/li>\n
  • Hypothalamic Modulation:<\/strong> Influences neuroendocrine control centers regulating behavior and hormonal responses.<\/li>\n
  • Central Mechanism of Action:<\/strong> Acts primarily within the central nervous system rather than peripheral tissues.<\/li>\n<\/ul>\n

    Supporting Study:<\/strong>
    Millington, G.W. \u2014 Peptides<\/em>
    PubMed \u2013 PMID: 18662530<\/p>\n

    \n

    2. Behavioral & CNS Pathway Research<\/strong><\/span><\/h4>\n
      \n
    • Dopaminergic Pathway Interaction:<\/strong> Modulates reward and motivation signaling pathways.<\/li>\n
    • Behavioral Response Modulation:<\/strong> Influences central behavioral outputs in experimental models.<\/li>\n
    • CNS Signaling Integration:<\/strong> Links melanocortin activity with broader neurochemical systems.<\/li>\n<\/ul>\n

      Supporting Study:<\/strong>
      Wessells, H. et al. \u2014 Journal of Urology<\/em>
      PubMed \u2013 PMID: 18639247<\/p>\n

      \n

      3. Endocrine & Hormonal Signaling Research<\/strong><\/span><\/h4>\n
        \n
      • Hormonal Regulation Pathways:<\/strong> Influences hypothalamic-pituitary signaling cascades.<\/li>\n
      • Interaction with Neurotransmitters:<\/strong> Connects peptide signaling with dopamine and other CNS mediators.<\/li>\n
      • Integrated Neuroendocrine Effects:<\/strong> Supports research into hormone-behavior relationships.<\/li>\n<\/ul>\n

        Supporting Study:<\/strong>
        Pfaus, J.G. et al. \u2014 Hormones and Behavior<\/em>
        PubMed \u2013 PMID: 16942757<\/p>\n

        \n

        Recommended Research Concentrations<\/strong><\/span><\/h3>\n
        \n
        \n\n\n\n\n\n\n\n
        Research Model<\/th>\nSuggested Concentration<\/th>\nAdministration<\/th>\n<\/tr>\n<\/thead>\n
        In-vitro receptor assays<\/td>\n1\u2013100 nM<\/td>\nAssay buffer<\/td>\n<\/tr>\n
        Neuronal signaling studies<\/td>\n1\u201350 \u00b5M<\/td>\nCell culture media<\/td>\n<\/tr>\n
        Animal models (rodents, SC)<\/td>\n0.1\u20131 mg\/kg<\/td>\nInjection<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<\/div>\n
        \n

        Why Choose Primal Research for Your PT-141 Studies?<\/strong><\/span><\/h3>\n
          \n
        • \u226598% HPLC-verified purity \u2014 critical for melanocortin receptor binding and CNS studies<\/li>\n
        • Independent third-party batch testing with COA available on request<\/li>\n
        • Lyophilized powder for maximum stability and long-term storage<\/li>\n
        • Available in 10mg quantity \u2014 supports controlled neuroendocrine and behavioral research protocols<\/li>\n<\/ul>\n
          \n

          Storage & Handling<\/strong><\/span><\/h3>\n
            \n
          • Store at -20\u00b0C, desiccated, and protected from light<\/li>\n
          • Soluble in sterile water or bacteriostatic water<\/li>\n
          • Prepare fresh solutions prior to each experiment<\/li>\n
          • Avoid repeated freeze-thaw cycles<\/li>\n<\/ul>\n
            \n

            Technical Specifications<\/strong><\/span><\/h3>\n

            Compound:<\/strong> PT-141 (Bremelanotide)
            Molecular Weight:<\/strong> ~1025 g\/mol
            Purity:<\/strong> \u226598% (HPLC Verified)
            Form:<\/strong> Lyophilized powder \u2014 available in 10mg
            Storage:<\/strong> -20\u00b0C, desiccated, light-protected
            Solubility:<\/strong> Soluble in sterile water or bacteriostatic water
            COA:<\/strong> Available per batch on request<\/p>\n

            \n

            Advance Your Neuroendocrine Research<\/strong><\/span><\/h3>\n

            Order your PT-141 10mg today to support advanced research in melanocortin signaling, CNS biology, and behavioral science.<\/p>\n

            \n

            Final Disclaimer:<\/strong>
            Primal Research products are sold strictly for in-vitro and laboratory research use only. Not for human or veterinary consumption. Not intended to diagnose, treat, cure, or prevent any disease or condition. Purchasers are responsible for compliance with all applicable local, state, and federal regulations.<\/p>\n","protected":false},"excerpt":{"rendered":"

            Primal Research products are sold strictly for in-vitro and laboratory research use only. Not for human or veterinary consumption. Not intended to diagnose, treat, cure, or prevent any disease or condition. Purchasers are responsible for compliance with all applicable local, state, and federal regulations.<\/p>\n","protected":false},"featured_media":492,"template":"","meta":{"_acf_changed":false},"product_brand":[],"product_cat":[82],"product_tag":[],"class_list":["post-523","product","type-product","status-publish","has-post-thumbnail","product_cat-melanocortin-research","pa_packaging-10mg","first","instock","shipping-taxable","purchasable","product-type-variable"],"acf":[],"_links":{"self":[{"href":"https:\/\/primalre.dalult4.hostarmada.net\/newwebsite\/wp-json\/wp\/v2\/product\/523","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/primalre.dalult4.hostarmada.net\/newwebsite\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/primalre.dalult4.hostarmada.net\/newwebsite\/wp-json\/wp\/v2\/types\/product"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/primalre.dalult4.hostarmada.net\/newwebsite\/wp-json\/wp\/v2\/media\/492"}],"wp:attachment":[{"href":"https:\/\/primalre.dalult4.hostarmada.net\/newwebsite\/wp-json\/wp\/v2\/media?parent=523"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/primalre.dalult4.hostarmada.net\/newwebsite\/wp-json\/wp\/v2\/product_brand?post=523"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/primalre.dalult4.hostarmada.net\/newwebsite\/wp-json\/wp\/v2\/product_cat?post=523"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/primalre.dalult4.hostarmada.net\/newwebsite\/wp-json\/wp\/v2\/product_tag?post=523"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}