{"id":528,"date":"2026-03-31T23:42:46","date_gmt":"2026-03-31T23:42:46","guid":{"rendered":"https:\/\/primalre.dalult4.hostarmada.net\/newwebsite\/?post_type=product&#038;p=528"},"modified":"2026-09-02T20:30:12","modified_gmt":"2026-09-02T20:30:12","slug":"tb-500","status":"publish","type":"product","link":"https:\/\/primalre.dalult4.hostarmada.net\/newwebsite\/product\/tb-500\/","title":{"rendered":"TB-500"},"content":{"rendered":"<h2 data-section-id=\"6kga42\" data-start=\"144\" data-end=\"224\"><span role=\"text\"><strong data-start=\"147\" data-end=\"224\">TB-500 | Thymosin Beta-4 Analog for Tissue Repair &amp; Regenerative Research<\/strong><\/span><\/h2>\n<p data-start=\"226\" data-end=\"415\">\u25a0 For Research Use Only. Not for human or veterinary use. Not a drug, supplement, or food additive.<br data-start=\"325\" data-end=\"328\" \/>Intended exclusively for in-vitro and laboratory research by qualified investigators.<\/p>\n<p data-start=\"417\" data-end=\"534\"><strong data-start=\"417\" data-end=\"434\">TB-500 \u2013 10mg<\/strong><br data-start=\"434\" data-end=\"437\" \/><strong data-start=\"437\" data-end=\"450\">Category:<\/strong> Peptide Research Compounds \/ Regenerative Biology \/ Tissue Repair &amp; Wound Healing<\/p>\n<hr data-start=\"536\" data-end=\"539\" \/>\n<h3 data-section-id=\"jn3j7p\" data-start=\"541\" data-end=\"559\"><span role=\"text\"><strong data-start=\"545\" data-end=\"559\">Disclaimer<\/strong><\/span><\/h3>\n<p data-start=\"561\" data-end=\"668\">ATTENTION: PRIMALRESEARCHLABS.COM PRODUCTS ARE INTENDED FOR LABORATORY RESEARCH AND IN-VITRO STUDIES ONLY.<\/p>\n<p data-start=\"670\" data-end=\"788\">All information presented on this site is for educational and research purposes related to scientific investigation.<\/p>\n<p data-start=\"790\" data-end=\"893\">These products are strictly not for human or veterinary use, consumption, or diagnostic applications.<\/p>\n<p data-start=\"895\" data-end=\"966\">They are not pharmaceuticals, food additives, or dietary supplements.<\/p>\n<p data-start=\"968\" data-end=\"1232\">By purchasing from PrimalResearchLabs.com, you acknowledge that you are a qualified researcher operating in a controlled laboratory environment and agree to follow all applicable local, state, and federal laws regarding the handling and use of research chemicals.<\/p>\n<p data-start=\"1234\" data-end=\"1342\">Handle all materials with appropriate personal protective equipment (PPE) and laboratory safety protocols.<\/p>\n<hr data-start=\"1344\" data-end=\"1347\" \/>\n<h3 data-section-id=\"bnrx5r\" data-start=\"1349\" data-end=\"1364\"><span role=\"text\"><strong data-start=\"1353\" data-end=\"1364\">Biology<\/strong><\/span><\/h3>\n<p data-start=\"1366\" data-end=\"1515\">TB-500 is a synthetic peptide analog of thymosin beta-4 (T\u03b24), a naturally occurring actin-binding protein widely distributed in mammalian tissues.<\/p>\n<p data-start=\"1517\" data-end=\"1638\">Thymosin beta-4 plays a key role in cell migration, angiogenesis, inflammation regulation, and tissue repair processes.<\/p>\n<p data-start=\"1640\" data-end=\"1833\">TB-500 has been extensively studied in preclinical models for its ability to promote wound healing, enhance cell migration, and support tissue regeneration across multiple biological systems.<\/p>\n<p data-start=\"1835\" data-end=\"2051\">Its ability to regulate actin polymerization and cellular movement makes it a valuable tool for in-vitro and in-vivo experimental design in musculoskeletal research, wound healing studies, and regenerative biology.<\/p>\n<p data-start=\"2053\" data-end=\"2176\">This product is intended solely for in-vitro and preclinical research use and is not for human or veterinary consumption.<\/p>\n<hr data-start=\"2178\" data-end=\"2181\" \/>\n<h3 data-section-id=\"1rpcc69\" data-start=\"2183\" data-end=\"2216\"><span role=\"text\"><strong data-start=\"2187\" data-end=\"2216\">Key Research Applications<\/strong><\/span><\/h3>\n<h4 data-start=\"2218\" data-end=\"2259\"><span role=\"text\"><strong data-start=\"2223\" data-end=\"2259\">1. Tissue Repair &amp; Wound Healing<\/strong><\/span><\/h4>\n<ul data-start=\"2261\" data-end=\"2585\">\n<li data-section-id=\"bet6w2\" data-start=\"2261\" data-end=\"2388\"><strong data-start=\"2263\" data-end=\"2294\">Cell Migration Enhancement:<\/strong> Promotes migration of keratinocytes, fibroblasts, and endothelial cells to sites of injury.<\/li>\n<li data-section-id=\"ucsdlb\" data-start=\"2389\" data-end=\"2495\"><strong data-start=\"2391\" data-end=\"2421\">Accelerated Wound Closure:<\/strong> Improves wound contraction and healing dynamics in experimental models.<\/li>\n<li data-section-id=\"16x2pmg\" data-start=\"2496\" data-end=\"2585\"><strong data-start=\"2498\" data-end=\"2528\">Tissue Remodeling Support:<\/strong> Enhances regeneration and structural repair processes.<\/li>\n<\/ul>\n<p data-start=\"2587\" data-end=\"2693\"><strong data-start=\"2587\" data-end=\"2608\">Supporting Study:<\/strong><br data-start=\"2608\" data-end=\"2611\" \/>Malinda, K.M. \u2014 <em data-start=\"2627\" data-end=\"2665\">Journal of Investigative Dermatology<\/em><br data-start=\"2665\" data-end=\"2668\" \/>PubMed \u2013 PMID: 12813045<\/p>\n<hr data-start=\"2695\" data-end=\"2698\" \/>\n<h4 data-start=\"2700\" data-end=\"2742\"><span role=\"text\"><strong data-start=\"2705\" data-end=\"2742\">2. Angiogenesis &amp; Vascular Growth<\/strong><\/span><\/h4>\n<ul data-start=\"2744\" data-end=\"3035\">\n<li data-section-id=\"1j8v3n6\" data-start=\"2744\" data-end=\"2837\"><strong data-start=\"2746\" data-end=\"2778\">Endothelial Cell Activation:<\/strong> Stimulates endothelial cell migration and proliferation.<\/li>\n<li data-section-id=\"1egy5gz\" data-start=\"2838\" data-end=\"2929\"><strong data-start=\"2840\" data-end=\"2867\">Angiogenesis Promotion:<\/strong> Enhances formation of new blood vessels in damaged tissues.<\/li>\n<li data-section-id=\"1eqkunp\" data-start=\"2930\" data-end=\"3035\"><strong data-start=\"2932\" data-end=\"2953\">VEGF Interaction:<\/strong> Supports pathways associated with vascular endothelial growth factor signaling.<\/li>\n<\/ul>\n<p data-start=\"3037\" data-end=\"3109\"><strong data-start=\"3037\" data-end=\"3058\">Supporting Study:<\/strong><br data-start=\"3058\" data-end=\"3061\" \/>Smart, N. \u2014 <em data-start=\"3073\" data-end=\"3081\">Nature<\/em><br data-start=\"3081\" data-end=\"3084\" \/>PubMed \u2013 PMID: 15538371<\/p>\n<hr data-start=\"3111\" data-end=\"3114\" \/>\n<h4 data-start=\"3116\" data-end=\"3167\"><span role=\"text\"><strong data-start=\"3121\" data-end=\"3167\">3. Anti-Inflammatory &amp; Cellular Protection<\/strong><\/span><\/h4>\n<ul data-start=\"3169\" data-end=\"3449\">\n<li data-section-id=\"1ft0a61\" data-start=\"3169\" data-end=\"3266\"><strong data-start=\"3171\" data-end=\"3208\">Inflammatory Response Modulation:<\/strong> Regulates cytokine expression and reduces inflammation.<\/li>\n<li data-section-id=\"2rhadt\" data-start=\"3267\" data-end=\"3359\"><strong data-start=\"3269\" data-end=\"3293\">Cellular Protection:<\/strong> Protects tissues from secondary damage during repair processes.<\/li>\n<li data-section-id=\"ywfp4q\" data-start=\"3360\" data-end=\"3449\"><strong data-start=\"3362\" data-end=\"3385\">Fibrosis Reduction:<\/strong> May influence pathways associated with scar tissue formation.<\/li>\n<\/ul>\n<p data-start=\"3451\" data-end=\"3565\"><strong data-start=\"3451\" data-end=\"3472\">Supporting Study:<\/strong><br data-start=\"3472\" data-end=\"3475\" \/>Goldstein, A.L. \u2014 <em data-start=\"3493\" data-end=\"3537\">Annals of the New York Academy of Sciences<\/em><br data-start=\"3537\" data-end=\"3540\" \/>PubMed \u2013 PMID: 12740123<\/p>\n<hr data-start=\"3567\" data-end=\"3570\" \/>\n<h3 data-section-id=\"15pq9l4\" data-start=\"3572\" data-end=\"3615\"><span role=\"text\"><strong data-start=\"3576\" data-end=\"3615\">Recommended Research Concentrations<\/strong><\/span><\/h3>\n<div class=\"TyagGW_tableContainer\">\n<div class=\"group TyagGW_tableWrapper flex flex-col-reverse w-fit\" tabindex=\"-1\">\n<table class=\"w-fit min-w-(--thread-content-width)\" data-start=\"3617\" data-end=\"3921\">\n<thead data-start=\"3617\" data-end=\"3678\">\n<tr data-start=\"3617\" data-end=\"3678\">\n<th class=\"\" data-start=\"3617\" data-end=\"3634\" data-col-size=\"sm\">Research Model<\/th>\n<th class=\"\" data-start=\"3634\" data-end=\"3660\" data-col-size=\"sm\">Suggested Concentration<\/th>\n<th class=\"\" data-start=\"3660\" data-end=\"3678\" data-col-size=\"sm\">Administration<\/th>\n<\/tr>\n<\/thead>\n<tbody data-start=\"3738\" data-end=\"3921\">\n<tr data-start=\"3738\" data-end=\"3803\">\n<td data-start=\"3738\" data-end=\"3771\" data-col-size=\"sm\">In-vitro cell migration assays<\/td>\n<td data-start=\"3771\" data-end=\"3781\" data-col-size=\"sm\">1\u201310 \u00b5M<\/td>\n<td data-col-size=\"sm\" data-start=\"3781\" data-end=\"3803\">Cell culture media<\/td>\n<\/tr>\n<tr data-start=\"3804\" data-end=\"3860\">\n<td data-start=\"3804\" data-end=\"3828\" data-col-size=\"sm\">Wound healing studies<\/td>\n<td data-start=\"3828\" data-end=\"3838\" data-col-size=\"sm\">1\u201320 \u00b5M<\/td>\n<td data-start=\"3838\" data-end=\"3860\" data-col-size=\"sm\">Cell culture media<\/td>\n<\/tr>\n<tr data-start=\"3861\" data-end=\"3921\">\n<td data-start=\"3861\" data-end=\"3894\" data-col-size=\"sm\">Animal models (rodents, SC\/IP)<\/td>\n<td data-col-size=\"sm\" data-start=\"3894\" data-end=\"3908\">0.1\u20132 mg\/kg<\/td>\n<td data-col-size=\"sm\" data-start=\"3908\" data-end=\"3921\">Injection<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<\/div>\n<hr data-start=\"3923\" data-end=\"3926\" \/>\n<h3 data-section-id=\"108skpp\" data-start=\"3928\" data-end=\"3987\"><span role=\"text\"><strong data-start=\"3932\" data-end=\"3987\">Why Choose Primal Research for Your TB-500 Studies?<\/strong><\/span><\/h3>\n<ul data-start=\"3989\" data-end=\"4298\">\n<li data-section-id=\"7ri5y2\" data-start=\"3989\" data-end=\"4074\">\u226598% HPLC-verified purity \u2014 critical for cell migration and tissue repair studies<\/li>\n<li data-section-id=\"z3koyq\" data-start=\"4075\" data-end=\"4146\">Independent third-party batch testing with COA available on request<\/li>\n<li data-section-id=\"1a996h7\" data-start=\"4147\" data-end=\"4213\">Lyophilized powder for maximum stability and long-term storage<\/li>\n<li data-section-id=\"v9bn4r\" data-start=\"4214\" data-end=\"4298\">Available in 10mg quantity \u2014 supports controlled regenerative research protocols<\/li>\n<\/ul>\n<hr data-start=\"4300\" data-end=\"4303\" \/>\n<h3 data-section-id=\"3yqf9y\" data-start=\"4305\" data-end=\"4331\"><span role=\"text\"><strong data-start=\"4309\" data-end=\"4331\">Storage &amp; Handling<\/strong><\/span><\/h3>\n<ul data-start=\"4333\" data-end=\"4532\">\n<li data-section-id=\"zxcces\" data-start=\"4333\" data-end=\"4388\">Store at -20\u00b0C, desiccated and protected from light<\/li>\n<li data-section-id=\"19iv2pd\" data-start=\"4389\" data-end=\"4441\">Soluble in sterile water or bacteriostatic water<\/li>\n<li data-section-id=\"la3m0a\" data-start=\"4442\" data-end=\"4494\">Prepare fresh solutions prior to each experiment<\/li>\n<li data-section-id=\"1jakekk\" data-start=\"4495\" data-end=\"4532\">Avoid repeated freeze-thaw cycles<\/li>\n<\/ul>\n<hr data-start=\"4534\" data-end=\"4537\" \/>\n<h3 data-section-id=\"gqkziz\" data-start=\"4539\" data-end=\"4571\"><span role=\"text\"><strong data-start=\"4543\" data-end=\"4571\">Technical Specifications<\/strong><\/span><\/h3>\n<p data-start=\"4573\" data-end=\"4888\"><strong data-start=\"4573\" data-end=\"4586\">Compound:<\/strong> TB-500 (Thymosin Beta-4 Analog)<br data-start=\"4618\" data-end=\"4621\" \/><strong data-start=\"4621\" data-end=\"4642\">Molecular Weight:<\/strong> ~4963 g\/mol<br data-start=\"4654\" data-end=\"4657\" \/><strong data-start=\"4657\" data-end=\"4668\">Purity:<\/strong> \u226598% (HPLC Verified)<br data-start=\"4689\" data-end=\"4692\" \/><strong data-start=\"4692\" data-end=\"4701\">Form:<\/strong> Lyophilized powder \u2014 10mg<br data-start=\"4727\" data-end=\"4730\" \/><strong data-start=\"4730\" data-end=\"4742\">Storage:<\/strong> -20\u00b0C, desiccated, light-protected<br data-start=\"4777\" data-end=\"4780\" \/><strong data-start=\"4780\" data-end=\"4795\">Solubility:<\/strong> Soluble in sterile water or bacteriostatic water<br data-start=\"4844\" data-end=\"4847\" \/><strong data-start=\"4847\" data-end=\"4855\">COA:<\/strong> Available per batch on request<\/p>\n<hr data-start=\"4890\" data-end=\"4893\" \/>\n<h3 data-section-id=\"1tj8mv\" data-start=\"4895\" data-end=\"4937\"><span role=\"text\"><strong data-start=\"4899\" data-end=\"4937\">Advance Your Regenerative Research<\/strong><\/span><\/h3>\n<p data-start=\"4939\" data-end=\"5057\">Order your TB-500 10mg today to support advanced research in tissue repair, angiogenesis, and wound healing biology.<\/p>\n<hr data-start=\"5059\" data-end=\"5062\" \/>\n<p data-start=\"5064\" data-end=\"5397\"><strong data-start=\"5064\" data-end=\"5085\">Final Disclaimer:<\/strong><br data-start=\"5085\" data-end=\"5088\" \/>Primal Research products are sold strictly for in-vitro and laboratory research use only. Not for human or veterinary consumption. Not intended to diagnose, treat, cure, or prevent any disease or condition. Purchasers are responsible for compliance with all applicable local, state, and federal regulations.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Primal Research products are sold strictly for in-vitro and laboratory research use only. Not for human or veterinary consumption. Not intended to diagnose, treat, cure, or prevent any disease or condition. Purchasers are responsible for compliance with all applicable local, state, and federal regulations.<\/p>\n","protected":false},"featured_media":482,"template":"","meta":{"_acf_changed":false},"product_brand":[],"product_cat":[80],"product_tag":[],"class_list":["post-528","product","type-product","status-publish","has-post-thumbnail","product_cat-tissue-cellular-research","pa_packaging-10mg","first","instock","featured","shipping-taxable","purchasable","product-type-variable"],"acf":[],"_links":{"self":[{"href":"https:\/\/primalre.dalult4.hostarmada.net\/newwebsite\/wp-json\/wp\/v2\/product\/528","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/primalre.dalult4.hostarmada.net\/newwebsite\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/primalre.dalult4.hostarmada.net\/newwebsite\/wp-json\/wp\/v2\/types\/product"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/primalre.dalult4.hostarmada.net\/newwebsite\/wp-json\/wp\/v2\/media\/482"}],"wp:attachment":[{"href":"https:\/\/primalre.dalult4.hostarmada.net\/newwebsite\/wp-json\/wp\/v2\/media?parent=528"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/primalre.dalult4.hostarmada.net\/newwebsite\/wp-json\/wp\/v2\/product_brand?post=528"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/primalre.dalult4.hostarmada.net\/newwebsite\/wp-json\/wp\/v2\/product_cat?post=528"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/primalre.dalult4.hostarmada.net\/newwebsite\/wp-json\/wp\/v2\/product_tag?post=528"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}