{"id":531,"date":"2026-03-31T23:47:28","date_gmt":"2026-03-31T23:47:28","guid":{"rendered":"https:\/\/primalre.dalult4.hostarmada.net\/newwebsite\/?post_type=product&p=531"},"modified":"2026-09-02T20:27:49","modified_gmt":"2026-09-02T20:27:49","slug":"semax","status":"publish","type":"product","link":"https:\/\/primalre.dalult4.hostarmada.net\/newwebsite\/product\/semax\/","title":{"rendered":"Semax"},"content":{"rendered":"

Semax | ACTH Analog Peptide for Cognitive & Neuroprotection Research<\/strong><\/span><\/h2>\n

\u25a0 For Research Use Only. Not for human or veterinary use. Not a drug, supplement, or food additive.
Intended exclusively for in-vitro and laboratory research by qualified investigators.<\/p>\n

Semax \u2013 30mg<\/strong>
Category:<\/strong> Peptide Research Compounds \/ Neuroscience Research \/ Cognitive & Neuroprotective Biology<\/p>\n

\n

Disclaimer<\/strong><\/span><\/h3>\n

ATTENTION: PRIMALRESEARCHLABS.COM PRODUCTS ARE INTENDED FOR LABORATORY RESEARCH AND IN-VITRO STUDIES ONLY.<\/p>\n

All information presented on this site is for educational and research purposes related to scientific investigation.<\/p>\n

These products are strictly not for human or veterinary use, consumption, or diagnostic applications.<\/p>\n

They are not pharmaceuticals, food additives, or dietary supplements.<\/p>\n

By purchasing from PrimalResearchLabs.com, you acknowledge that you are a qualified researcher operating in a controlled laboratory environment and agree to follow all applicable local, state, and federal laws regarding the handling and use of research chemicals.<\/p>\n

Handle all materials with appropriate personal protective equipment (PPE) and laboratory safety protocols.<\/p>\n

\n

Biology<\/strong><\/span><\/h3>\n

Semax is a synthetic heptapeptide derived from the adrenocorticotropic hormone (ACTH 4\u201310) fragment. It has been modified to enhance stability and biological activity while lacking hormonal side effects associated with full-length ACTH.<\/p>\n

Semax has been extensively studied in preclinical and clinical research models for its neuroprotective, cognitive-enhancing, and neurotrophic properties.<\/p>\n

It modulates brain-derived neurotrophic factor (BDNF) expression, influences dopaminergic and serotonergic pathways, and enhances synaptic plasticity.<\/p>\n

Its stability and central nervous system activity make it a valuable tool for in-vitro and in-vivo experimental design across cognitive research, neuroprotection studies, and CNS signaling pathway investigations.<\/p>\n

This product is intended solely for in-vitro and preclinical research use and is not for human or veterinary consumption.<\/p>\n

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Key Research Applications<\/strong><\/span><\/h3>\n

1. Cognitive Function & Neurotrophic Signaling<\/strong><\/span><\/h4>\n
    \n
  • BDNF Expression Modulation:<\/strong> Increases brain-derived neurotrophic factor, supporting neuronal growth and survival.<\/li>\n
  • Synaptic Plasticity Enhancement:<\/strong> Improves signaling pathways involved in learning and memory.<\/li>\n
  • Cognitive Performance Models:<\/strong> Studied in experimental models of memory and attention.<\/li>\n<\/ul>\n

    Supporting Study:<\/strong>
    Grivennikov, I.A. \u2014 Bulletin of Experimental Biology and Medicine<\/em>
    PubMed \u2013 PMID: 18097726<\/p>\n

    \n

    2. Neuroprotection & Ischemic Brain Research<\/strong><\/span><\/h4>\n
      \n
    • Ischemic Protection:<\/strong> Protective effects in cerebral ischemia models.<\/li>\n
    • Neuronal Survival Support:<\/strong> Reduces neuronal damage and promotes recovery.<\/li>\n
    • Anti-Excitotoxic Effects:<\/strong> Modulates glutamate-mediated neurotoxicity.<\/li>\n<\/ul>\n

      Supporting Study:<\/strong>
      Gusev, E.I. \u2014 Neuroscience and Behavioral Physiology<\/em>
      PubMed \u2013 PMID: 11830742<\/p>\n

      \n

      3. Neurotransmitter Modulation & CNS Signaling<\/strong><\/span><\/h4>\n
        \n
      • Dopaminergic Pathway Regulation:<\/strong> Influences dopamine signaling associated with motivation and cognition.<\/li>\n
      • Serotonergic Interaction:<\/strong> Modulates serotonin pathways involved in mood and behavior.<\/li>\n
      • CNS Integration:<\/strong> Supports balanced neurotransmitter activity in experimental models.<\/li>\n<\/ul>\n

        Supporting Study:<\/strong>
        Zozulya, A.A. \u2014 Neuroscience and Behavioral Physiology<\/em>
        PubMed \u2013 PMID: 15201974<\/p>\n

        \n

        Recommended Research Concentrations<\/strong><\/span><\/h3>\n
        \n
        \n\n\n\n\n\n\n\n
        Research Model<\/th>\nSuggested Concentration<\/th>\nAdministration<\/th>\n<\/tr>\n<\/thead>\n
        In-vitro neuronal assays<\/td>\n1\u2013100 nM<\/td>\nCell culture media<\/td>\n<\/tr>\n
        Cognitive pathway studies<\/td>\n1\u201350 \u00b5M<\/td>\nCell culture media<\/td>\n<\/tr>\n
        Animal models (rodents, IN\/IP)<\/td>\n0.1\u20131 mg\/kg<\/td>\nIntranasal or injection<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<\/div>\n
        \n

        Why Choose Primal Research for Your Semax Studies?<\/strong><\/span><\/h3>\n
          \n
        • \u226598% HPLC-verified purity \u2014 critical for neurotrophic signaling and CNS pathway studies<\/li>\n
        • Independent third-party batch testing with COA available on request<\/li>\n
        • Lyophilized powder for maximum stability and long-term storage<\/li>\n
        • Available in 10mg quantity \u2014 supports controlled neuroscience and neuroprotection research protocols<\/li>\n<\/ul>\n
          \n

          Storage & Handling<\/strong><\/span><\/h3>\n
            \n
          • Store at -20\u00b0C, desiccated and protected from light<\/li>\n
          • Soluble in sterile water or bacteriostatic water<\/li>\n
          • Prepare fresh solutions prior to each experiment<\/li>\n
          • Avoid repeated freeze-thaw cycles<\/li>\n<\/ul>\n
            \n

            Technical Specifications<\/strong><\/span><\/h3>\n

            Compound:<\/strong> Semax
            Molecular Weight:<\/strong> ~813.9 g\/mol
            Purity:<\/strong> \u226598% (HPLC Verified)
            Form:<\/strong> Lyophilized powder \u2014 10mg
            Storage:<\/strong> -20\u00b0C, desiccated, light-protected
            Solubility:<\/strong> Soluble in sterile water or bacteriostatic water
            COA:<\/strong> Available per batch on request<\/p>\n

            \n

            Advance Your Neuroscience Research<\/strong><\/span><\/h3>\n

            Order your Semax 10mg today to support advanced research in cognitive function, neuroprotection, and CNS biology.<\/p>\n

            \n

            Final Disclaimer:<\/strong>
            Primal Research products are sold strictly for in-vitro and laboratory research use only. Not for human or veterinary consumption. Not intended to diagnose, treat, cure, or prevent any disease or condition. Purchasers are responsible for compliance with all applicable local, state, and federal regulations.<\/p>\n","protected":false},"excerpt":{"rendered":"

            Primal Research products are sold strictly for in-vitro and laboratory research use only. Not for human or veterinary consumption. Not intended to diagnose, treat, cure, or prevent any disease or condition. Purchasers are responsible for compliance with all applicable local, state, and federal regulations.<\/p>\n","protected":false},"featured_media":1009,"template":"","meta":{"_acf_changed":false},"product_brand":[],"product_cat":[81],"product_tag":[],"class_list":["post-531","product","type-product","status-publish","has-post-thumbnail","product_cat-neuropeptide-research","pa_packaging-30mg","first","instock","shipping-taxable","purchasable","product-type-variable"],"acf":[],"_links":{"self":[{"href":"https:\/\/primalre.dalult4.hostarmada.net\/newwebsite\/wp-json\/wp\/v2\/product\/531","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/primalre.dalult4.hostarmada.net\/newwebsite\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/primalre.dalult4.hostarmada.net\/newwebsite\/wp-json\/wp\/v2\/types\/product"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/primalre.dalult4.hostarmada.net\/newwebsite\/wp-json\/wp\/v2\/media\/1009"}],"wp:attachment":[{"href":"https:\/\/primalre.dalult4.hostarmada.net\/newwebsite\/wp-json\/wp\/v2\/media?parent=531"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/primalre.dalult4.hostarmada.net\/newwebsite\/wp-json\/wp\/v2\/product_brand?post=531"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/primalre.dalult4.hostarmada.net\/newwebsite\/wp-json\/wp\/v2\/product_cat?post=531"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/primalre.dalult4.hostarmada.net\/newwebsite\/wp-json\/wp\/v2\/product_tag?post=531"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}