{"id":545,"date":"2026-03-31T23:58:10","date_gmt":"2026-03-31T23:58:10","guid":{"rendered":"https:\/\/primalre.dalult4.hostarmada.net\/newwebsite\/?post_type=product&p=545"},"modified":"2026-09-02T20:34:28","modified_gmt":"2026-09-02T20:34:28","slug":"ghk-cu","status":"publish","type":"product","link":"https:\/\/primalre.dalult4.hostarmada.net\/newwebsite\/product\/ghk-cu\/","title":{"rendered":"GHK-CU"},"content":{"rendered":"

Copper-Binding Tripeptide Complex | Tissue Repair & Regenerative Biology Research Compound<\/strong><\/span><\/h2>\n
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\u25a0 For Research Use Only. Not for human or veterinary use. Not a drug, supplement, or food additive.<\/p>\n

Intended exclusively for in-vitro and laboratory research by qualified investigators.<\/p>\n

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GHK-Cu \u2013 50mg \u2013 A Copper-Binding Tripeptide for Tissue Repair and Regenerative Research<\/strong><\/p>\n

Category:<\/strong> Peptide Research Compounds \/ Regenerative Biology \/ Tissue Repair & Skin Biology<\/p>\n

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Disclaimer:<\/strong><\/span><\/h2>\n

ATTENTION: PRIMALRESEARCHLABS.COM PRODUCTS ARE INTENDED FOR LABORATORY RESEARCH AND IN-VITRO STUDIES ONLY.<\/p>\n

All information presented on this site is for educational and research purposes related to scientific investigation.<\/p>\n

These products are strictly not for human or veterinary use, consumption, or diagnostic applications.<\/p>\n

They are not pharmaceuticals, food additives, or dietary supplements.<\/p>\n

By purchasing from PrimalResearchLabs.com, you acknowledge and affirm that you are a qualified researcher operating in a controlled laboratory environment.<\/p>\n

You must adhere to all applicable local, state, and federal laws and regulations regarding the handling and use of research chemicals.<\/p>\n

Handle all materials with appropriate personal protective equipment (PPE) and under laboratory safety protocols.<\/p>\n

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Biology<\/strong><\/span><\/h2>\n

GHK-Cu (glycyl-L-histidyl-L-lysine copper complex) is a naturally occurring copper-binding tripeptide originally identified in human plasma and later detected in saliva and urine.<\/p>\n

It has been extensively studied in preclinical research for its role in tissue remodeling, wound repair, extracellular matrix regulation, and gene expression modulation.<\/p>\n

GHK-Cu is of particular interest in regenerative biology due to its reported ability to stimulate collagen synthesis, enhance fibroblast activity, regulate metalloproteinase expression, and promote angiogenesis in experimental models.<\/p>\n

Its broad biological activity and stability make it a versatile tool for in-vitro and in-vivo experimental design across skin biology, connective tissue research, and wound healing studies.<\/p>\n

This product is intended solely for in-vitro and preclinical research use and is not for human or veterinary consumption.<\/p>\n

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Key Research Applications of GHK-Cu<\/strong><\/span><\/h2>\n

Tissue Repair & Extracellular Matrix Remodeling Research<\/strong><\/span><\/h3>\n

GHK-Cu has demonstrated significant activity in tissue repair studies through:<\/p>\n

Collagen Synthesis Stimulation \u2014 Increases production of collagen types I and III and glycosaminoglycans in fibroblast culture systems.<\/p>\n

Fibroblast Activation \u2014 Enhances fibroblast proliferation and migration, supporting wound healing and dermal regeneration models.<\/p>\n

Matrix Remodeling Regulation \u2014 Modulates matrix metalloproteinases (MMPs) and their inhibitors, contributing to controlled extracellular matrix turnover.<\/p>\n

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Supporting Studies:<\/strong><\/span><\/h3>\n

Maquart, F.X. et al. \u2014 Biochimica et Biophysica Acta.<\/p>\n

\u201cCopper-peptide complexes stimulate accumulation of extracellular matrix components in cultured fibroblasts.\u201d<\/p>\n

\u25a0 PubMed \u2013 PMID: 3703959<\/p>\n

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Wound Healing & Angiogenesis Research<\/strong><\/span><\/h2>\n

GHK-Cu has been investigated for its role in tissue regeneration and vascular biology through:<\/p>\n

Accelerated Wound Healing \u2014 Associated with faster wound contraction and improved tissue organization in preclinical models.<\/p>\n

Angiogenesis Promotion \u2014 Stimulates vascular endothelial growth factor (VEGF) expression and capillary formation.<\/p>\n

Tissue Regeneration Support \u2014 Enhances granulation tissue formation and structural repair.<\/p>\n

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Supporting Studies:<\/strong><\/span><\/h3>\n

Pickart, L. et al. \u2014 Journal of Biomaterials Science.<\/p>\n

\u201cGHK-Cu promotes wound healing and angiogenesis through modulation of cellular signaling pathways.\u201d<\/p>\n

\u25a0 PubMed \u2013 PMID: 16412543<\/p>\n

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Anti-Inflammatory & Oxidative Stress Research<\/strong><\/span><\/h2>\n

GHK-Cu has been explored in oxidative stress and inflammation studies through:<\/p>\n

Cytokine Modulation \u2014 Reduces pro-inflammatory cytokines and supports balanced immune response signaling.<\/p>\n

Antioxidant Activity \u2014 Enhances endogenous antioxidant enzyme systems, including superoxide dismutase activity.<\/p>\n

Cellular Protection \u2014 Demonstrates protective effects against oxidative damage in stressed cellular environments.<\/p>\n

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Supporting Studies:<\/strong><\/span><\/h3>\n

Pickart, L. & Margolina, A. \u2014 International Journal of Molecular Sciences.<\/p>\n

\u201cGHK-Cu modulates gene expression associated with antioxidant defense, inflammation control, and tissue repair.\u201d<\/p>\n

\u25a0 PubMed \u2013 PMID: 29772703<\/p>\n

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Recommended Research Concentrations<\/strong><\/span><\/h2>\n

Note: For laboratory research reference only. Not for human or veterinary use.<\/p>\n

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Research Model<\/p>\n

Suggested Concentration<\/p>\n

Administration<\/p>\n

In-vitro fibroblast studies<\/p>\n

1\u201310 \u00b5M<\/p>\n

Cell culture media<\/p>\n

Wound healing assays<\/p>\n

1\u201320 \u00b5M<\/p>\n

Cell culture media<\/p>\n

Animal models (rodents, topical\/injection)<\/p>\n

0.1\u20131 mg\/kg<\/p>\n

Topical or injection<\/p>\n

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Why Choose Primal Research for Your GHK-Cu Research?<\/strong><\/span><\/h2>\n

\u226598% HPLC-verified purity \u2014 critical for gene expression and regenerative pathway studies<\/p>\n

Independent third-party batch testing with COA available on request<\/p>\n

Lyophilized powder for maximum stability and long-term storage<\/p>\n

Available in 50mg quantity \u2014 supports extended multi-phase research protocols<\/p>\n

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Storage & Handling<\/strong><\/span><\/h2>\n

Store at -20\u00b0C, desiccated and protected from light<\/p>\n

Soluble in sterile water or bacteriostatic water<\/p>\n

Prepare fresh solutions prior to each experiment<\/p>\n

Avoid repeated freeze-thaw cycles<\/p>\n

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Technical Specifications<\/strong><\/span><\/h2>\n

Compound: GHK-Cu (glycyl-L-histidyl-L-lysine copper complex)<\/p>\n

Molecular Weight: ~403.38 g\/mol<\/p>\n

Molecular Formula: C14H24CuN6O4<\/p>\n

Purity: \u226598% (HPLC Verified)<\/p>\n

Form: Lyophilized powder \u2014 available in 50mg<\/p>\n

Storage: -20\u00b0C, desiccated, light-protected<\/p>\n

Solubility: Soluble in sterile water or bacteriostatic water<\/p>\n

COA: Available per batch on request<\/p>\n

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Advance Your Regenerative Biology Research<\/strong><\/span><\/h2>\n

Order your GHK-Cu 50mg today to support advanced research in tissue repair, wound healing, and skin regeneration science.<\/p>\n

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Final Disclaimer:<\/strong><\/span><\/h2>\n

Primal Research products are sold strictly for in-vitro and laboratory research use only.<\/p>\n

Not for human or veterinary consumption.<\/p>\n

Not intended to diagnose, treat, cure, or prevent any disease or condition.<\/p>\n

Purchasers are responsible for compliance with all applicable local, state, and federal regulations.<\/p>\n","protected":false},"excerpt":{"rendered":"

Primal Research products are sold strictly for in-vitro and laboratory research use only. Not for human or veterinary consumption. Not intended to diagnose, treat, cure, or prevent any disease or condition. Purchasers are responsible for compliance with all applicable local, state, and federal regulations.<\/p>\n","protected":false},"featured_media":552,"template":"","meta":{"_acf_changed":false},"product_brand":[],"product_cat":[80],"product_tag":[],"class_list":["post-545","product","type-product","status-publish","has-post-thumbnail","product_cat-tissue-cellular-research","pa_packaging-50mg","first","instock","featured","shipping-taxable","purchasable","product-type-variable"],"acf":[],"_links":{"self":[{"href":"https:\/\/primalre.dalult4.hostarmada.net\/newwebsite\/wp-json\/wp\/v2\/product\/545","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/primalre.dalult4.hostarmada.net\/newwebsite\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/primalre.dalult4.hostarmada.net\/newwebsite\/wp-json\/wp\/v2\/types\/product"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/primalre.dalult4.hostarmada.net\/newwebsite\/wp-json\/wp\/v2\/media\/552"}],"wp:attachment":[{"href":"https:\/\/primalre.dalult4.hostarmada.net\/newwebsite\/wp-json\/wp\/v2\/media?parent=545"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/primalre.dalult4.hostarmada.net\/newwebsite\/wp-json\/wp\/v2\/product_brand?post=545"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/primalre.dalult4.hostarmada.net\/newwebsite\/wp-json\/wp\/v2\/product_cat?post=545"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/primalre.dalult4.hostarmada.net\/newwebsite\/wp-json\/wp\/v2\/product_tag?post=545"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}