Growth Hormone Releasing Hormone (GHRH) Analog | Endocrine & GH Axis Research Compound

For Research Use Only. Not for human or veterinary use. Not a drug, supplement, or food additive.

Intended exclusively for in-vitro and laboratory research by qualified investigators.

Sermorelin – 5mg
A GHRH (1–29) Analog for Growth Hormone Axis and Endocrine Research

Category: Peptide Research Compounds / Endocrinology Research / GH Axis Biology

Disclaimer

ATTENTION: PrimalResearchLabs.com products are intended for laboratory research and in-vitro studies only. All information is for educational and research purposes related to scientific investigation.

These products are strictly not for human or veterinary use, consumption, or diagnostic applications. They are not pharmaceuticals, food additives, or dietary supplements.

By purchasing from PrimalResearchLabs.com, you acknowledge that you are a qualified researcher operating in a controlled laboratory environment. Follow all applicable local, state, and federal laws regarding handling and use of research chemicals. Use appropriate PPE and follow laboratory safety protocols.

Biology

Sermorelin is a synthetic peptide representing the first 29 amino acids of endogenous growth hormone-releasing hormone (GHRH 1–29), the biologically active fragment responsible for stimulating GH secretion from the anterior pituitary.

Sermorelin stimulates physiologic pulsatile GH secretion, preserving natural regulatory feedback mechanisms within the hypothalamic-pituitary axis. Unlike exogenous GH administration, it promotes endogenous hormone production, making it a valuable tool for in-vitro and in-vivo studies across GH deficiency models, metabolic research, and endocrine pathway investigation.

This product is intended solely for in-vitro and preclinical research use and is not for human or veterinary consumption.

Key Research Applications of Sermorelin

1. Growth Hormone Secretion & GHRH Receptor Research

• GHRH Receptor Activation: Stimulates GH release via direct binding to pituitary GHRH receptors.
• Pulsatile GH Secretion: Preserves physiologic GH release patterns and feedback regulation.
• Endocrine Axis Integrity: Maintains hypothalamic-pituitary control mechanisms in research models.

Supporting Studies:
Thorner, M.O. et al. — Journal of Clinical Investigation
“GHRH (1–29) stimulates growth hormone release through specific receptor-mediated mechanisms.”
PubMed – PMID: 3086132

2. GH/IGF-1 Axis & Metabolic Regulation Research

• IGF-1 Production: Increases circulating IGF-1 via GH-mediated signaling.
• Metabolic Function Support: Influences lipid metabolism and glucose regulation pathways.
• Endocrine Response Modeling: Useful for GH-dependent metabolic studies.

Supporting Studies:
Gelato, M.C. et al. — Journal of Clinical Endocrinology & Metabolism
“Sermorelin stimulates GH secretion and increases IGF-1 levels in controlled endocrine studies.”
PubMed – PMID: 11701438

3. Aging & Endocrine Function Research

• Age-Related GH Decline: Investigated in models of reduced GH secretion associated with aging.
• Hormonal Balance Studies: Supports evaluation of endocrine system function over time.
• Physiologic Hormone Restoration Models: Used in studies examining restoration of natural GH rhythms.

Supporting Studies:
Corpas, E. et al. — Journal of Clinical Endocrinology & Metabolism
“Growth hormone-releasing hormone restores GH secretion in aging models.”
PubMed – PMID: 8188727

Recommended Research Concentrations

For laboratory research reference only. Not for human or veterinary use.

Why Choose Primal Research for Sermorelin?

• ≥98% HPLC-verified purity — critical for GHRH receptor binding and GH secretion studies
• Independent third-party batch testing with COA available
• Lyophilized powder for maximum stability and long-term storage
• Available in 5mg quantity — supports controlled endocrine research protocols

Storage & Handling

• Store at -20°C, desiccated, protected from light
• Soluble in sterile water or bacteriostatic water
• Prepare fresh solutions prior to each experiment
• Avoid repeated freeze-thaw cycles

Technical Specifications

• Compound: Sermorelin (GHRH 1–29)
• Molecular Weight: ~3357 g/mol
• Purity: ≥98% (HPLC Verified)
• Form: Lyophilized powder — available in 5mg
• Storage: -20°C, desiccated, light-protected
• Solubility: Soluble in sterile water or bacteriostatic water
• COA: Available per batch on request

Advance Your Endocrine Research

Order your Sermorelin 5mg today to support advanced research in growth hormone signaling, endocrine biology, and metabolic regulation.

Primal Research products are sold strictly for in-vitro and laboratory research use only. Not for human or veterinary consumption. Not intended to diagnose, treat, cure, or prevent any disease or condition. Purchasers are responsible for compliance with all applicable local, state, and federal regulations.